产品货号：
Z14717
中文名称：
Dapper homolog 2/DACT2抗体
英文名称：
Anti-Dapper homolog 2/DACT2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Dapper homolog 2/DACT2 Antibody |
| 指标别名 | DPR2,DAPPER2,C6orf116,bA503C24.7,PP13671,Dapper homolog 2,Dapper antagonist of catenin 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | DACT2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Dact2 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human DACT2.The immunogen is located within amino acids 150 - 200 of Dact2. |
| 计算分子量 | 83kDa |
| 成分 | Dact2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Dact2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases.Many members of this pathway are also expressed in the postnatal tissues such as brain.One such protein is Dact2,a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl),a cytoplasmic protein essential to Wnt signaling.Dact2 is most prominent during the development of the thymus kidneys,and salivary gland.Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling.Furthermore,Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors.At least two isoforms of Dact2 are known to exist. |
| Uniprot ID | Q5SW24 |
| 基因名全称 | Dapper,antagonist of beta-catenin,homolog 2 (Xenopus laevis) |
| 蛋白名全称 | Dapper,antagonist of beta-catenin,homolog 2 (Xenopus laevis) |
| 推荐稀释比 | Dact2 antibody can be used for detection of Dact2 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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